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Acute Coronary Syndromes
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Autor: K Sarat Chandra , AJ Swamy
Editura: CRC Press
Limba: Engleza
Nr. pagini: 224
Coperta: Paperback
Dimensiuni: 20.96 x 1.27 x 27.31 cm
An aparitie: 16 July 2020
Description:
Acute Coronary Syndrome (ACS) is a growing global menace with patients increasing in developing countries where tobacco and food play a major role. Its treatment guidelines and research results have proliferated in academia, but practical applications lag behind that research. This book addresses this void. Guidelines for treatment of ACS present in-depth reading for practicing cardiologists, thus preventing clinical application. The book aims to appraise readers of real-world situations and suggestions to help them acquire up-to-date knowledge on ACS and its effective diagnosis, prognosis and management. Key Features Covers recent advances in ACS management and pharmacotherapy Discusses the guidelines for treatment of ACS for the professional cardiologist to apply to clinical practice Explores the topics with the help of case scenarios Follows a concise, yet comprehensive approach Features a chapter on 'When to Transfer,' which discusses how to spot unstable patients or those heading towards shock
Table of Contents:
1. Epidemiology of acute coronary syndromes in India
India: Coronary capital of the world
Acute coronary syndromes in india
Geographic epidemiology
Clinical and pharmacoepidemiology
Genetic epidemiology
Conclusion
References
2. Pathophysiology of acute coronary syndrome
Introduction
Atherogenesis
Mechanisms of Thrombosis
Symptomology in Relation to Coronary Thrombi
Plaque Disruption: The Healing Process
In Vivo Culprit Lesion Assessment in ACS by Optical Coherence Tomography
Myocardial Infarction with Non-Obstructive Coronary Arteries
Conclusion
References
3. Current outcomes and outcome measures in acute coronary syndrome
Introduction
ST-Elevation Myocardial Infarction (STEMI)
Non-ST-Elevation Myocardial Infarction
Incidence and Outcomes in Contemporary Care
Risk Assessment in NSTEMI
Basic Management
Anti-Platelet Therapy
Anti-Coagulation
Invasive versus Conservative Management
Timing of Invasive Management
Culprit Vessel versus Multi-vessel PCI
PCI versus Coronary Artery Bypass Grafting
References
4. Clinical syndromes in acute coronary syndrome: Angina and its equivalents
Introduction
Pathophysiology
Chest Discomfort/Pain
Anginal Pain Equivalents
Atypical Presentations
Conclusion
References
5. ECG spectrum in acute coronary syndrome
ECG Spectrum in Acute Coronary Syndromes
ECG Diagnosis of Myocardial Infarction with Bundle Branch Blocks
Lead aVR in Acute Coronary Syndromes
Abnormal Q waves
Potential Confounders in ECG Changes in ACS
Anterior Wall ST-Elevation MI Equivalents
Myocardial Ischaemia and Repolarisation Changes
References
6. Arrhythmias in acute coronary syndrome
Introduction
Ventricular tachyarrhythmias
Supraventricular arrhythmias
Conclusion
References
7. Intravascular imaging in acute coronary syndrome
Introduction
Intravascular imaging modalities
Intravascular imaging: tissue characterisation
Intravascular imaging in ACS
Intravascular imaging-guided intervention to prevent no-reflow
Imaging-guided stent implantation
Conclusion
References
8. Cardiac biomarkers in acute coronary syndrome
Introduction
Traditional cardiac biomarkers
Conclusion
References
9. Risk stratification in acute coronary syndromes
Introduction
Determination of risk factors and pre-test assessment
ECG aspect
Stress test
Interventional aspect
Observational studies and using additional predictors
References
10. Initial therapy and when to transfer at non-pci centres
Doctor’s clinic or PHC
A secondary care centre or a community health centre (CHC) with AN ECG facility
A district hospital/secondary care centre where thrombolysis is possible
Conclusion
References
11. Anti-platelet therapy in acute coronary syndrome: What is current and new?
Currently approved oral anti-platelet agents in ACS
Intravenous anti-platelet agents in ACS
References
12. Current status of fibrinolytic therapy
Introduction
Indications of fibrinolytic therapy
Pre-hospital fibrinolysis
Late therapy
Choice of fibrinolytic agent
Intracoronary fibrinolysis
Adjunctive use of anti-platelets
Adjunctive use of antithrombotics
Hazards of fibrinolytic therapy
Contraindications of fibrinolysis
Transfer of patients after fibrinolysis
Choice of reperfusion therapy
References
13. Anti-coagulation in acute coronary syndrome
Introduction
Pathophysiology of ACS and role of anti-coagulation
Anti-coagulants used in ACS
Anti-coagulation in STEMI
Anti-coagulation in NSTEMI
Newer anti-coagulants in ACS
Guidelines
Future vision
Conclusion
References
14. Contentious issues in primary angioplasty: Deferred stenting, manual thrombectomy, culprit versus complete revascularisation, microvasculature in ACS
Manual thrombectomy
Deferred stenting
Culprit-only revascularisationversus complete revascularisation
Revascularisation in patients with cardiogenic shock
References
15. PCI post-thrombolysis: When and for whom?
Approach to the patient
References
16. PCI in unstable angina and NSTEMI
Introduction
Epidemiology and natural history
Pathophysiology
Diagnosis
Differential diagnosis
Risk assessment
Management
Conclusion
References
17. Bleeding in acute coronary syndrome
Introduction
Incidence and site of bleeding in ACS
Bleeding definitions
Risk factors for bleeding in ACS
Effect of drugs on bleeding in ACS
Adverse outcomes with bleeding in ACS
Management of bleeding in ACS
Prevention of bleeding in ACS
Conclusion
References
18. Statins in acute coronary syndrome
Introduction
Acute coronary syndrome
Statins and their actions
Guidelines
Conclusion
References
19. Intravenous anti-platelet therapy—GP IIb/IIIa blockers and cangrelor: What has changed recently?
Introduction
Timing and method of administration
Recent guidelines
Conclusion
References
20. CABG in acute coronary syndrome
CABG in non-st-elevation MI ACS
CABG in st-elevation MI
Timing of surgery
Anti-platelet/fibrinolytic therapy
Pre-operative management
Technical considerations
Outcomes of CABG in ACS
CABG versus PCI in ACS
Cardiogenic shock: recommendations
OPCAB in ACS
Mechanical circulatory support in ACS
Post-operative pharmacotherapy
Future
Conclusion
References
21. Acute coronary syndrome with haemodynamic instability
Introduction
Causes of haemodynamic instability in ACS
Pathophysiology
Clinical features
Investigations and diagnosis
Differential diagnosis
Management
conclusion
References
22. Acute coronary syndrome in special populations: Women, the elderly, chronic kidney disease and the young
Introduction
ACS in women
ACS in the elderly
ACS in CKD patients
Contrast-induced nephropathy (IN)
ACS in the young
Conclusion
References
23. Short-term rehabilitation after an acute coronary event
Benefits of cardiac rehabilitation after ACS
Components of cardiac rehabilitation after ACS
Conclusion
References
24. Acute coronary syndrome: Case-based scenarios
Introduction
Case scenario 1
Case scenario 2
Case scenario 3
Conclusion
References
25. Quality improvement programme for acute coronary syndrome care in India
Introduction
Brief history of cardiovascular health care quality improvement
Fundamental concepts related to quality, safety and quality improvement
Cardiovascular health care quality improvement programmes in ACS in India
Challenges, opportunities and future directions
Conclusion
Acknowledgement
References
26. Primary angioplasty: Basic principles
Introduction
Various treatment strategies for acute STEMI
Limitations of fibrinolysis
Primary PCI: Goals, time logistics, why and in which situations?
Basic terminologies related to primary PCI timing
Procedural aspects of interventions during PPCI
Prevention of distal embolisation in PPCI
Role of covered stents and distal embolisation devices in PPCI
Role of glycoprotein IIb/IIIa inhibitors (GPIs) in PPCI
Intracoronary pharmacotherapy in PPCI
Intracoronary fibrinolytics
Technical issues in primary PCI
Stenting in primary PCI
Selection of stent type in PPCI
Role of intra-Aortic balloon pump (IABP) in PPCI
Role of intracoronary imaging in PPCI
Primary PCI in special situations
PPCI in cardiogenic shock
Conclusion
References
27. Management of acute coronary syndromes in acute phase in India: Relevance of Western guidelines
Introduction
Clinical spectrum
Diagnosis and initial assessment
Risk stratification
Management strategies for NSTE-ACS
Guideline-mandated management strategies
Invasive coronary angiography and revascularisation
Revascularisation strategies
Relevance of the guidelines for clinical practice in india
Conclusion
References
Index
An aparitie | 16 July 2020 |
Autor | K Sarat Chandra , AJ Swamy |
Dimensiuni | 20.96 x 1.27 x 27.31 cm |
Editura | CRC Press |
Format | Paperback |
ISBN | 9780367112226 |
Limba | Engleza |
Nr pag | 224 |
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