Severe Pulmonary Emphysema:: A Comprehensive Guide to Precision Interventional Procedures

Chronic obstructive pulmonary disease is, of 2024, one of the three main causes of death in the world, affecting around 12% of the world's population. Its incidence is estimated to increase in the coming decades due to continuous exposure to risk factors and to an aging population.

Pulmonary emphysema is one of its most serious phenotypes, with chronic and inexorable progression and, in the most severe stages, it is highly disabling and lethal.

This book reviews knowledge about the pathophysiology of severe pulmonary emphysema and the current innovative interventional and minimally invasive therapeutic concepts for the management of these advanced stages of emphysema, based on the best scientific evidence.

This guide provides to multidisciplinary pulmonary boards of experts in advanced lung diseases, current criteria for the choice of precision therapeutic options and beyond to maintaining optimized medical treatment to controlling lung hyperinflation, and alleviating patients' symptoms.

This book is a valuable resource for clinicians dealing with critically ill patients with COPD.

Table of Contents:

Chapter 1. Pathophysiology of Emphysema

José R. Jardim

Chapter 2. Pulmonary Functional Evaluation for Safe Performance of BLVR

Jin Sun Kim and Gerard J. Criner

Chapter 3 The concept of lung volume reduction and the best evidence

Nathaniel Marchetti and Gerard J. Criner

Chapter 4. Surgical Concept and Technique of Lung Volume Reduction Surgery

Laurens J. Ceulemans, Christelle M. Vandervelde, Claudio Caviezel and Walter Weder

Chapter 5. Image Analysis to Identify Target Areas for Lung Volume Reduction

Maruti Kumaran, Yogesh Gupta and Chandra Dass

Chapter 6. Nuclear Medicine Techniques in Pre-evaluation of Single Pulmonary Nodule Resection, Lung Volume Reduction Surgery and Pre and Post Bronchoscopic Lung Volume Reduction

Sean Ide Bolet, Gerard Criner and Simin Dadparvar

Chapter 7. The Precision Treatment for Severe Lung Emphysema and the Impact of the Multidisciplinary Lung Board

Luis C. Losso, Marina Dornfeld C. Castro, Mario C. Ghefter and Marcel M. Sandrini

Chapter 8. The Current Optimized Medical Treatment and the Impact on Dynamic Hyperinflation

José R. Jardim

Chapter 9. Lung Volume Reduction Surgery: Technique, Tips and Challenges

Andrew Akcelik and Charles T. Bakhos

Chapter 10. Extending Candidacy for Lung Volume Reduction Surgery

Claudio Caviezel, Laurens Ceulemans and Walter Weder

Chapter 11. The Interface Lung Emphysema and Lung Cancer

Mario C. Ghefter, Ricardo S. Santos and Luis C. Losso

Chapter 12. Bronchoscopic Lung Volume Reduction Innovations

Justin L. Garner and Pallav L. Shah

Chapter 13. Peri-Interventional Clinical Management of Endoscopic Emphysema Treatment

Johannes Wienker and Kaid Darwiche

Chapter 14. Bronchoscopic Lung Volume Reduction with One-Way Valves: Prevention and Management of Complications

T. David Koster, Hugo G. Oliveira and Dirk-Jan Slebos

Chapter 15. Pulmonary Rehabilitation for COPD Patients

José R. Jardim

Chapter 16. Results and Long-Term Follow Up of Interventional Treatments for Lung Emphysema: Quality of Life Considerations

Alexey Abramov, Mark E. Ginsburg and Bryan P. Stanifer

Chapter 17. The Future of Treating Hyperinflation in Emphysema

Justin L Garner and Pallav L Shah