DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology

The standard-setting text in oncology for 40 years, DeVita, Hellman and Rosenberg's Cancer: Principles and Practice of Oncology, 12th Edition, provides authoritative guidance and strategies for managing every type of cancer by stage and presentation. Drs. Vincent T. DeVita, Jr., Theodore S. Lawrence, and Steven A. Rosenberg oversee an outstanding team of expert contributing authors who keep you up to date and fully informed in this fast-changing field. This award-winning reference is also continually updated on Health Library and VitalSource platforms for the life of the edition.

• Integrates basic science into individual cancer chapters for more efficient reference
• Features quarterly updates that include late-breaking developments in oncology such as new drugs and clinical trials, as well as new case studies and interactive algorithms
• Offers balanced, multidisciplinary advice from a surgeon, a medical oncologist, and a radiation oncologist
• Provides updated content on immunotherapy and genetics throughout
• Includes important related topics such as cancer screening and prevention, palliative care, supportive oncology, and quality of life issues
• Now available in a convenient single volume, or a seven-multivolume option for portability and ease of use

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Table of Contents:

Cover

Editors

Title Page

Copyright

Contributing Authors

Preface

Acknowledgements

Contents

PART I Etiology and Prevention of Cancer

1. Global Cancer Incidence and Mortality

2. Tobacco Use and the Cancer Patient

3. Lifestyle Factors

4. Genetic Counseling & Testing

PART II Cancer Therapeutics

5. Essentials of Radiation Therapy

6. Alkylating Agents

7. Platinum Analogs

8. Antimetabolites

9. Topoisomerase-Interacting Agents

10. Microtubule Inhibitors

11. Kinase Inhibitors as Anticancer Drugs

12. Histone Deacetylase Inhibitors, Demethylating Agents, and Epigenetic Drugs

13. Proteasome Inhibitors

14. Poly(ADP-Ribose) Polymerase Inhibitors for Tumors with Defects in DNA Repair

15. Miscellaneous Chemotherapeutic Agents

16. Hormonal Agents

17. Immunotherapy Agents: Monoclonal Antibodies

18. Immunotherapy Agents: Checkpoint Modulators

19. Immunotherapy Agents: Cellular Therapies

20. Immunotherapy Agents: Nonspecific Stimulators

21. Allogeneic Stem Cell Transplantation

PART III Practice of Oncology

22. Design and Analysis of Clinical Trials

23. General Principles in the Management of Head and Neck Cancer

24. Cancer of the Nasopharynx

25. Cancer of the Larynx and Hypopharynx

26. Oropharynx Cancer

27. Cancer of the Oral Cavity

28. Cancer of the Nasal Vestibule, Nasal Cavity, and Paranasal Sinuses

29. Cancer of the Salivary Gland

30. Non–small-cell Lung Cancer

31. Small Cell and Neuroendocrine Tumors of the Lung

32. Neoplasms of the Mediastinum

33. Cancer of the Esophagus

34. Cancer of the Stomach

35. Cancer of the Pancreas

36. Cancer of the Liver

37. Cancer of the Biliary Tree

38. Small Bowel Cancer

39. Gastrointestinal Stromal Tumor

40. Cancer of the Colon

41. Cancer of the Rectum

42. Cancer of the Anal Region

43. Cancer of the Kidney

44. Cancer of the Bladder, Ureter, and Renal Pelvis

45. Cancer of the Prostate

46. Cancer of the Urethra and Penis

47. Cancer of the Testis

48. Cancer of the Cervix

49. Cancer of the Vagina and Vulva

50. Cancer of the Uterine Body

51. Gestational Trophoblastic Neoplasia

52. Ovarian Cancer

53. Malignant Tumors of the Breast

54. Thyroid Tumors

55. Parathyroid Tumors

56. Adrenal Tumors

57. Pancreatic Neuroendocrine Neoplasms

58. Carcinoid Tumors and the Carcinoid Syndrome

59. Multiple Endocrine Neoplasia

60. Soft Tissue Sarcoma

61. Sarcomas of Bone

62. Cancer of the Skin

63. Cutaneous Melanoma

64. Neoplasms of the Central Nervous System

65. Adolescents and Young Adults with Cancer

66. Hodgkin Lymphoma

67. Non-Hodgkin Lymphoma

68. Cutaneous Lymphomas

69. Primary Central Nervous System Lymphoma

70. Management of Acute Leukemias

71. Chronic Myeloid Leukemia

72. Chronic Lymphocytic Leukemias

73. Myelodysplastic Syndromes

74. Plasma Cell Neoplasms

75. Cancer of Unknown Primary

76. Benign and Malignant Mesothelioma

77. Peritoneal Metastases and Peritoneal Mesothelioma

78. Intraocular Melanoma

79. Superior Vena Cava Syndrome

80. Increased Intracranial Pressure

81. Spinal Cord Compression

82. Metabolic Emergencies

83. Metastatic Cancer to the Brain

84. Metastatic Cancer to the Lungs

85. Metastatic Cancer to the Liver

86. Metastatic Cancer to the Bone

87. Malignant Pleural and Pericardial Effusions

88. Malignant Ascites

89. Paraneoplastic Syndromes

90. Neutropenia and Thrombocytopenia

91. Nausea and Vomiting

92. Diarrhea and Constipation

93. Oral Complications

94. Cardiac Toxicity

95. Gonadal Dysfunction

96. Fatigue

97. Neurocognitive Effects

98. Management of Cancer Pain

99. Nutrition Support

100. Sexual Problems

101. Psychiatric Distress and Resilience

102. How We Talk to Patients and How We Talk to Ourselves

103. Specialized Care of the Terminally Ill

Part IV Societal Issues

104. Cancer Survivorship

105. Minority Health and Cancer Health Disparities

106. Virtual Care and Telehealth in Oncology

107. Complementary, Alternative, and Integrative Therapies in Cancer Care

Index