Biopsy Interpretation of the Gastrointestinal Tract Mucosa: Volume 2: Neoplastic (Biopsy Interpretation Series)

Your instant access VST eBook comes with a comprehensive quiz that provides experience with high-yield, board-style teaching questions and answers PLUS 200 additional images for additional perspectives of entities covered in the print book. One of the best-selling titles in the highly regarded Biopsy Interpretation Series, Biopsy Interpretation of the Gastrointestinal Tract Mucosa Volume 1: Non-Neoplastic, Fourth Edition, by Drs. Lysandra Voltaggio and Elizabeth A. Montgomery, provides practical, highly illustrated information on mucosal biopsies from the esophagus, stomach, small intestine, large intestine, and anus. Well-organized and highly readable, this fully revised volume offers the information you need to successfully navigate both common and unusual issues that arise in the day-to-day interpretation of gastrointestinal biopsies. Volume One focuses on non-neoplastic entities; also available is Volume Two, your complete guide to neoplastic gastrointestinal lesions.

Table of Contents:

1 Esophagus

INTRODUCTION

INLET PATCH (CERVICAL GASTRIC HETEROTOPIA)

PANCREATIC ACINAR CELL METAPLASIA/HETEROTOPIA

HETEROTOPIC SEBACEOUS GLANDS

ESOPHAGEAL MELANOCYTOSIS/MELANOSIS

GLYCOGENIC ACANTHOSIS

ESOPHAGEAL LEUKOPLAKIA/EPIDERMOID METAPLASIA

Findings in Mechanical Disorders

REFLUX DISEASE

ALLERGIC/EOSINOPHILIC ESOPHAGITIS

Pathophysiology and Demographics

Symptoms

Endoscopic Findings

Histologic Findings

INJURY DUE TO CHEMICAL OR PHYSICAL AGENTS AND MEDICATIONS

Iron

Kayexalate

Bile Acid Sequestrants (Colesevelam, Cholestyramine, and Colestipol)

Sevelamer (Renvela)

Taxane Effect

Colchicine Toxicity

Mycophenolate

Fosamax

Doxycycline

Immune Checkpoint Inhibitors

ESOPHAGITIS DISSECANS SUPERFICIALIS/“THERMAL INJURY”/“SLOUGHING ESOPHAGITIS”

CORROSIVE INGESTION

ATYPICAL STROMAL CELLS IN ULCERS/POLYPS

MULTINUCLEATED EPITHELIAL GIANT CELL CHANGE

GRAFT-VERSUS-HOST DISEASE

DERMATOLOGIC DISEASE AFFECTING THE ESOPHAGUS

Lichen Planus

Pityriasis Lichenoides

Bullous Diseases

ESOPHAGITIS FROM INFECTIOUS AGENTS

Viral Esophagitis: Cytomegalovirus and Herpes (Simplex and Zoster)

Syphilis

Fungal Esophagitis: Candida

Bacterial Esophagitis

HIV-Associated Ulcers

CROHN DISEASE AFFECTING THE ESOPHAGUS

LYMPHOCYTIC ESOPHAGITIS

COMMON VARIABLE IMMUNODEFICIENCY

Systemic Amyloidosis

2 Stomach

INTRODUCTION

ACUTE HEMORRHAGIC GASTRITIS

CHEMICAL GASTRITIS/REACTIVE GASTROPATHY

MUCOSAL CALCINOSIS

LANTHANUM

PROTON PUMP INHIBITOR EFFECTS

INJURY DUE TO CHEMICAL AGENTS, IATROGENIC INJURY, AND DRUGS

Iron

Gastric Siderosis

Pseudomelanosis

Kayexalate

Colchicine and Taxol-Associated Changes

Mycophenolate

Yttrium

Corrosive Injury

Chemoradiation-Associated Injury

Injury Associated With Immune Checkpoint Inhibitors

HELICOBACTER GASTRITIS

INACTIVE CHRONIC GASTRITIS

PHLEGMONOUS GASTRITIS

METAPLASTIC ATROPHIC GASTRITIS

Autoimmune Metaplastic Atrophic Gastritis

Environmental Metaplastic Atrophic Gastritis

Gastric Changes in Autoimmune Enteropathy/Immune Dysfunction, Polyendocrinopathy, Enteropathy, and X-Linked Inheritance and Related Conditions

Atrophic Autoimmune Pangastritis

Mid- and Deep Zone Gastritis

GASTRIC ANTRAL VASCULAR ECTASIA

PORTAL GASTROPATHY

DIEULAFOY LESION

GASTRITIS CYSTICA POLYPOSA/PROFUNDA

LYMPHOCYTIC GASTRITIS

COLLAGENOUS GASTRITIS

FOCALLY ENHANCED GASTRITIS (INFLAMMATORY BOWEL DISEASE PATTERN)

GRANULOMATOUS GASTRITIS

OTHER INFLAMMATORY CONDITIONS

Eosinophilic Gastritis

Olmesartan

Syphilis Gastritis

Cytomegalovirus Gastritis and Epstein-Barr–Associated Gastritis

Russell Body Gastritis

Gastric Findings in Common Variable Immunodeficiency

Gastric Graft Versus Host Disease

HYPERPLASTIC/HYPERTROPHIC GASTRITIS

Foveolar Hyperplasia

Hyperplasia of Oxyntic Glands

AMYLOIDOSIS AND OTHER SYSTEMIC DISEASES

3 Small Intestine

INTRODUCTION

“ARTIFACTS” MISTAKEN FOR OTHER LESIONS

REACTIVE LESIONS

INFECTIOUS ENTERITIS

Mycobacterium avium Complex

Whipple Disease

Strongyloides Infection

Giardiasis

Other Agents and Granulomatous Enteritis

PSEUDOMELANOSIS DUODENI

ISCHEMIC DISEASE: YTTRIUM-90

MEDICATION-ASSOCIATED INJURY AND OTHER IATROGENIC FORMS OF INJURY

Lanthanum

Olmesartan (Benicar) and Other Angiotensin II Receptor Antagonists

Nivolumab, Pembrolizumab (PD-1 Inhibitors), and Ipilimumab (Anti-CTLA-4)

Nonsteroidal Anti-Inflammatory Drugs

Graft Versus Host Disease

Mycophenolate-Associated Injury

Colchicine Toxicity

MALABSORPTION

Celiac Disease

Refractory Celiac Disease/Sprue and Collagenous Sprue

NK-Cell Enteropathy

IgA Deficiency

Hypobetalipoproteinemia and Abetalipoproteinemia

Tropical Sprue

Small-Bowel Bacterial Overgrowth

CROHN DISEASE

BEHÇET DISEASE

CRYPTOGENIC MULTIFOCAL ULCEROUS STENOSING ENTERITIS

SMALL INTESTINAL FINDINGS IN ULCERATIVE COLITIS

AMYLOIDOSIS

COMMON VARIABLE IMMUNODEFICIENCY

AUTOIMMUNE ENTEROPATHY

PEDIATRIC ENTEROPATHIES

LYMPHATIC AND VASCULAR CONDITIONS

Lymphangiectasia

PORTAL HYPERTENSIVE DUODENOPATHY

HENOCH-SCHONLEIN PURPURA (IGA VASCULITIS)

4 Colon

INTRODUCTION

COLON HISTOLOGY

IRRITABLE BOWEL SYNDROME

EFFECTS OF BOWEL PREPARATION AND OTHER ARTIFACTS

OTHER ENDOSCOPIC AND BIOPSY-RELATED ARTIFACTS

FOCAL ACTIVE COLITIS

LAMINA PROPRIA MACROPHAGES

REACTIVE CHANGES THAT CAN MIMIC NEOPLASIA

Signet Ring Cell Change

Atypical Stromal Cells

IDIOPATHIC INFLAMMATORY BOWEL DISEASE

ULCERATIVE COLITIS

CROHN DISEASE

Very Early- and Late Onset-IBD

POUCHITIS

CUFFITIS

EOSINOPHILIC COLITIS

INFECTIOUS COLITIS

Acute Self-Limited Colitis

Neutropenic Enterocolitis

Colonic Spirochetosis

Infections Notorious for Mimicking Inflammatory Bowel Disease

Sexually Transmitted Infections

Protozoan Infections

Fungal Infections

Viral Infections

Mycobacteria

HIV-Associated Giant Cells

Malakoplakia

Parasites

ISCHEMIC COLITIS

FINDINGS IN SYSTEMIC DISEASES

Scleroderma

Vasculitis

Idiopathic Myointimal Hyperplasia of Mesenteric Veins

Autoimmune Enterocolopathy

Amyloidosis

Mastocytosis

Langerhans Cell Histiocytosis

Common Variable Immunodeficiency

Absent Plasma Cells in the Setting of CAR T-Cell Therapy

Chronic Granulomatous Disease

IATROGENIC INJURY

Radiation Colitis/Proctitis

Mycophenolate (Cellcept)-Associated Colonic Injury

Immune Checkpoint Inhibitor-Associated Injury (Ipilimumab, Pembrolizumab, Nivolumab, Atezolizumab, Durvalumab, Avelumab)

Idelalisib-Associated Injury

Secukinumab (Cosentyx)

Crystals: Kayexalate (Sodium Polystyrene Sulfonate), Bile Acid Sequestrants, Sevelamer, Crospovidone, and Microcrystalline Cellulose

Graft Versus Host Disease

Cord Colitis

Diversion Colitis

MICROSCOPIC COLITIS

MISCELLANEOUS CONDITIONS

Diverticular Disease–Associated Colitis

Handling Aganglionosis Cases

CHANGES IN CYSTIC FIBROSIS

5 Anus

INTRODUCTION

HEMORRHOIDS

PAPILLARY ENDOTHELIAL HYPERPLASIA (VEGETANT INTRAVASCULAR HEMANGIOENDOTHELIOMA)

INFECTIOUS PROCTITIS

Herpes Simplex Virus

Cytomegalovirus

Syphilis

Lymphogranuloma Venereum

CONDYLOMA- AND HUMAN PAPILLOMAVIRUS-ASSOCIATED LESIONS

CROHN DISEASE

Index

Interactive Question Bank