Samaranayake’s Essential Microbiology for Dentistry

 

A sound knowledge of microbiology is essential for all dental professionals – it’s the key to understanding major oral pathologies, from tooth decay to gum disease, as well as the regimentation of infection control in a successful dental practice. Samaranayake’s Essential Microbiology for Dentistry once again, provides a comprehensive coverage of the basics of clinical oral microbiology and immunology and their relevance to oral disease, as well as the cotemporary discoveries of the oral microbiome, and the constituent flora. Both the novice student, as well as the experienced professionals are guided, in a stepwise manner, through a tour of the microbial world and how they impact oral health. The reasoned, bare bones approach to the essential elements of the subject is, as in previous editions fresh, lucid and logical. The sixth edition of this popular book, now translated into four different languages, has been fully revised and reformatted and includes brand new sections on emerging topics such as COVID-19 and infection control.

Latest evidence throughout, updated to incorporate discoveries appertaining to the oral microbiome, and the international guidelines on infection control.

Ample artwork and clinical pictures to explain complex structures, intricate pathological processes, and disease management principles.

Friendly accessible writing style that helps students better understand and retain key information.

Self-assessment tasks to monitor progress and prepare for graduate and postgraduate examinations

Easy to follow - highlighted important information, and helpful summaries of key facts.

A comprehensive glossary and a list of abbreviations

Definitions and descriptors of the oralome, the oral microbiome and oral microbiota - revealed by novel, next-generation sequencing technologies

SARS-CoV-2 infection, the COVID-19 pandemic, and its impact on dentistry

MPox and other emerging viral infections and oral manifestations

Oral mycobiome and emerging and re-emerging oral fungal diseases

Oral microbiota, the oral-systemic axis and systemic health

Antimicrobial resistance (AMR) and its mitigation by good antimicrobial prescribing

The recently proclaimed `One health` concept basics

A guide to new vaccines and immunisation protocols

Extended and fully updated sections on infection control

 

Table of Contents:

 

Online Study for Students

1 Why Study Microbiology?

A Note on Emerging and Re-emerging Infections

About This Book

Further Reading

Part 1 General microbiology

2 Bacterial Structure and Taxonomy

Eukaryotes and Prokaryotes

Morphology

Taxonomy

Review Questions (Answers on p. 388)

Further Reading

3 Bacterial Physiology and Genetics

Bacterial Physiology

Bacterial Genetics

Recombinant DNA Technology in Microbiology

The Era of ‘-omics’

Review Questions (answers on p. 388)

Further Reading

4 Viruses and Prions

Structure

Taxonomy

Viral Replication

Pathogenesis of Viral Infections

Cellular Antiviral Response

Prions and Prion Diseases

Review Questions (answers on p. 388)

Further Reading

5 Pathogenesis of Microbial Disease

General Aspects of Infection

Pathogenesis of Bacterial Disease

Pathogenesis of Viral Disease

Pathogenesis of Fungal Disease

Koch’s Postulates

Review Questions (Answers on p. 388)

Further Reading

6 Diagnostic Microbiology and Laboratory Methods

Diagnostic Microbiology

Laboratory Methods

Bacterial Identification

Immunological Methods

Laboratory Investigations Related to Antimicrobial Therapy

Appropriate Specimens in Medical Microbiology

Laboratory Isolation and Identification of Viruses

Diagnosis of Fungal Infections

Review Questions (Answers on p. 388)

Further Reading

7 Antimicrobial Chemotherapy

Bacteriostatic and Bactericidal Antimicrobial Agents

Principles of Antimicrobial Therapy

Pharmacodynamics of Antimicrobials

Failure of Antimicrobial Therapy

Antimicrobials Commonly Used in Dentistry

Antibacterial Agents

Antifungal Agents

Antiviral Agents

Review Questions (Answers on p. 388)

Further Reading

Part 2 Basic immunology

8 The Immune System and the Oral Cavity

The Immune System: General Considerations

The Innate Immune System

The Adaptive Immune System

Cells of the Immune System

Oral Defence Mechanisms

Innate Immune Mechanisms

The Oral Mucosal Epithelium

Adaptive Immunity in Oral Health and Disease

Review Questions (Answers on p. 388)

Further Reading

9 The Immune Response

Antibodies

Cytokines

B Cell Activation

Antigen Processing and Presentation

T-Helper Subsets

Target Cell Killing

Activation of Macrophages

Regulation of the Immune Response

Immunological Memory

Review Questions (Answers on p. 389)

Further Reading

10 Immunity and Infection

Immunity to Bacteria

Immunity to Viruses

Immunity to Parasites

Immunity to Fungi

Vaccination

‘-omics’ Developments Impacting Oral Immunology

Review Questions (Answers on p. 389)

Further Reading

Part 3 Microbes of relevance to dentistry

11 Streptococci, Staphylococciand Enterococci

Streptococci

Staphylococci

Enterococci

Micrococci

Review Questions (Answers on p. 389)

Further Reading

12 Lactobacilli, Corynebacteria and Propionibacteria

Lactobacilli

Corynebacteria

Propionibacteria

Review Questions (Answers on p. 389)

Further Reading

13 Actinomycetes, Clostridia and Bacillus Species

Actinomycetes

Nocardia

Clostridia

Bacillus

Review Questions (Answers on p. 389)

Further Reading

14 Neisseriaceae, Veillonella, Parvobacteria and Capnocytophaga

Neisseriaceae

Veillonella

Parvobacteria

Haemophilus Species

Bordetella

Review Questions (Answers on p. 389)

Further Reading

15 Enterobacteria

General Characteristics of Enterobacteria

Eschericheae

Salmonellae

Shigellae

Klebsielleae

Pseudomonads

Review Questions (Answers on p. 389)

Further Reading

16 Vibrios, Campylobacters and Wolinella

Vibrios

Campylobacters

Wolinella

Review Questions (Answers on p. 390)

Further Reading

17 Bacteroides, Tannerella, Porphyromonas and Prevotella

Bacteroides

Tannerella

Porphyromonas

Prevotella

Review Questions (Answers on p. 390)

Further Reading

18 Fusobacteria, Leptotrichia and Spirochaetes

Fusobacteria

Leptotrichia

Spirochaetes

Treponema

Borrelia

Leptospira

Review Questions (Answers on p. 390)

Further Reading

19 Mycobacteria and Legionellae

Mycobacteria

Legionella

Further Reading

Review Questions (Answers on p. 390)

20 Chlamydiae, Rickettsiae and Mycoplasmas

Chlamydiae

Rickettsiae

Mycoplasmas

Further Reading

Review Questions (Answers on p. 390)

21 Viruses of Relevance to Dentistry

DNA Viruses

RNA Viruses

Viruses and Cancer

Further Reading

Review Questions (Answers on p. 390)

22 Fungi of Relevance to Dentistry

Morphology

Reproduction

Classification

Cultural Requirements

Pathogenicity

Human Mycoses

Yeasts

Filamentous and Dimorphic Fungi and Oral Disease

Review Questions (Answers on p. 390)

Further Reading

Part 4 Systemic Infections of relevance to dentistry

23 Infections of the Respiratory Tract

Normal Flora

Important Pathogens of the Respiratory Tract

Infections of the Upper Respiratory Tract

Infections of the Paranasal Sinuses and the Middle Ear

Infections of the Trachea and Bronchi

Lung Infections

Severe Acute Respiratory Syndrome (SARS) and Coronavirus Disease 2019 (COVID-19)

Fungal Infections of the Lower Respiratory Tract

Respiratory Infections and Dentistry

Review Questions (Answers on p. 390)

Further Reading

24 Infections of the Cardiovascular System

Bacteraemia, Septicaemia and Sepsis Syndrome

Infections of the Heart

British and US Guidelines on Prophylaxis Against Infective Endocarditis in Patients Undergoing Interventional Procedures

Dental Procedures That Need Antibiotic Prophylaxis

Review Questions (Answers on p. 390)

Further Reading

25 Infections of the Central Nervous and Locomotor Systems

Infections of the Central Nervous System

Infections of the Locomotor System

Arthroplasties and Antibiotic Prophylaxis for Dental Procedures

Review Questions (Answers on p. 391)

Further Reading

26 Infections of the Gastrointestinal Tract

Normal Flora

Common Diarrhoeal Diseases

Less Common and Uncommon Diarrhoeal Diseases

Nonbacterial Causes of Diarrhoea

Review Questions (Answers on p. 391)

Further Reading

27 Infections of the Genitourinary Tract

Normal Flora and the Natural Defences of the Genitourinary Tract

Sexually Transmitted Infections

Urinary Tract Infections

Dentistry and Genitourinary Infections

Review Questions (Answers on p. 391)

Further Reading

28 Skin and Wound Infections

Normal Flora

Skin Infections

Wound Infections

Review Questions (Answers on p. 391)

Further Reading

29 Viral Hepatitis

Signs and Symptoms of Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D (Delta Hepatitis)

Hepatitis E

Hepatitis Viruses of Unclear Pathogenicity

Review Questions (Answers on p. 391)

Further Reading

30 Human Immunodeficiency Virus Infection, AIDS and Infections in Compromised Patients

Human Immunodeficiency Virus Infection and Acquired Immune Deficiency Syndrome

Human Immunodeficiency Virus

Acquired Immune Deficiency Syndrome

Prevention of HIV Infection

Infections in Compromised Patients

Xerostomia and Infection

Review Questions (Answers on p. 391)

Further Reading

Part 5 Oral microbiota and oral infections

31 Oral Microbiota and the Oralome

Oral Microbiome and the Oral Microbiota

Oral Microbiota

Oral Bacteriome

Oral Mycobiome

Oral Virome

Oral Phageome

Oral Archaeome

Oral Protozome

The Oral Ecosystem

The Plaque Biofilm

Review Questions (Answers on p. 391)

Further Reading

32 Microbiology of Dental Caries

Epidemiology

Classifications

Diagnosis

Aetiology

Management of Dental Caries

Review Questions (Answers on p. 392)

Further Reading

33 Microbiology of Periodontal Disease

The Periodontium

Classification of Periodontal Disease

The Progression From Gingivitis to Periodontitis

Relationship Between Chronic Marginal Gingivitis and Periodontitis

Acute Necrotizing Ulcerative Gingivitis (ANUG)

Pericoronitis

Peri-implant Microbiology

Clinical Implications of Microbiological Tests in Periodontal Disease

Review Questions (Answers on p. 392)

Further Reading

34 Dentoalveolar and Endodontic Infections

Natural History of Dentoalveolar Infections

Source of Microorganisms

Apical Dentoalveolar Abscess

Ludwig’s Angina

Pericoronitis (See Chapter 33.)

Periodontal Abscess

Suppurative Osteomyelitisof the Jaws

Cervicofacial Actinomycosis

Facial Lacerations

Endodontic Infections

Review Questions (answers on p. 392)

Further Reading

35 Oral Mucosal and Salivary Gland Infections

Oral Mucosal Infections

Oral Manifestations of Systemic Mycoses

Oral Viral Infections

Oral Manifestations of Bacterial Infections

Salivary Gland Infections

Review Questions (Answers on p. 392)

Further Reading

Part 6 Cross-infection and control

36 General Principles of Infection Control, Standard Precautions and Transmission-Based Precautions

General Principles of Infection Control

Routes of Infection

Standard Infection Control Precautions

Review Questions (Answers on p. 392)

Further Reading

37 Standard Infection Control Procedures in Dentistry Part I: Personal Protection, Sharps Injuries Protocol and Immunization

Practice Management and Staff Development

Infection Control: Specific Practical Features

Review Questions (Answers on p. 392)

Further Reading

38 Standard Infection Control Procedures in Dentistry Part II: Sterilization, Disinfection and Antisepsis, with a Summary of Transmission-Based Infection Control Procedures

Sterilization, Disinfection and Antisepsis

Decontamination

Decontamination of Instruments

Sterilization

Disinfection

Step 1

Step 2

Environmental Disinfection

Dental Unit Water Lines: Disinfection and Management

Recommendations on Care of Handpieces and Other Devices Attached to Air and Water Lines

Dental Radiology

Laboratory Asepsis

Office/Surgery Design and Maintenance

Instrument Recirculation and Office Design

Disposal of Clinical Waste

Transmission-Based Precautions

Contact Precautions: For Ambulatory Clinic Settings

Droplet Precautions: For Ambulatory Clinic Settings

Airborne Precautions: For Ambulatory Clinic Settings

Review Questions (Answers on p. 392)

Further Reading

Answers to Review Questions

Glossary of Terms and Abbreviations

Index

 

An aparitie	16 apr 2024
Autor	Lakshman Samaranayake
Dimensiuni	216 x 276 mm
Editura	Elsevier
Format	Paperback
ISBN	9780443117213
Limba	Engleza
Nr pag	424