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Quick Guide to Kidney Transplantation
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Autor: Dr. Phuong-Chi T. Pham MD
Editura: Lippincott Williams and Wilkins
Limba: Engleza
Nr. pagini: 352
Coperta: Paperback
Dimensiuni: 6 x 0.5 x 9 inches
An aparitie: 2019
· 1. Transplant Immunobiology
· ABO BLOOD GROUP ANTIGENS
· MAJOR HISTOCOMPATIBILITY COMPLEX, HUMAN LEUKOCYTE ANTIGEN MOLECULES
· HUMAN LEUKOCYTE ANTIGEN–TYPING TECHNIQUES
· Serotyping
· DNA typing
· Human leukocyte antigen nomenclature
· MINOR HISTOCOMPATIBILITY ANTIGEN
· NON–HUMAN LEUKOCYTE ANTIGENS
· ALLORECOGNITION PATHWAYS: DIRECT, INDIRECT, AND SEMIDIRECT ALLORECOGNITION
· HUMAN LEUKOCYTE ANTIGEN ALLOSENSITIZATION
· TECHNIQUES FOR DETECTION OF ANTI–HUMAN LEUKOCYTE ANTIGEN ANTIBODIES: GENERAL CONCEPTS
· CELL-BASED CYTOTOXICITY PANEL REACTIVE ANTIBODY ASSAY
· SOLID-PHASE ASSAYS USING LUMINEX TECHNOLOGY
· PRETRANSPLANTATION CROSSMATCH
· VIRTUAL CROSSMATCH
· IMMUNOLOGIC EVALUATION OF THE TRANSPLANT CANDIDATES
· REFERENCES
· 2. Immunosuppression
· THE THREE-SIGNAL MODEL OF ALLOIMMUNE RESPONSES
· TARGETS OF VARIOUS IMMUNOSUPPRESSIVE AGENTS
· BASIC PRINCIPLES OF AN IMMUNOSUPPRESSIVE PROTOCOL
· SIDE EFFECT PROFILES, DRUG-DRUG INTERACTIONS, NURSING AND DIETARY CONSIDERATIONS
· OTHER IMMUNOSUPPRESSIVE AGENTS (ALSO SUMMARIZED IN CHAPTER 3)
· REFERENCES
· 3. Allograft Rejection: Types and Treatment Strategies
· ALLOGRAFT REJECTION: HYPERACUTE, ACUTE, AND CHRONIC
· Hyperacute rejection
· Acute rejection
· Chronic rejection
· TREATMENT OF ACUTE REJECTION
· Overview
· Treatment of acute T cell–mediated rejection based on Banff classification
· Treatment of chronic active T cell–mediated rejection
· Treatment of acute antibody-mediated rejection
· Donor-specific antibody testing after plasmapheresis or plasma exchange to assess treatment response
· IVIG and rituximab recycling process
· Treatment of chronic active antibody-mediated rejection
· Manipulation of maintenance immunosuppression following treatment of acute T cell–mediated rejection or acute antibody-mediated rejection
· Suggested prophylactic antibiotics and antiviral therapy following treatment of acute rejection episodes (practice may vary among transplant centers)
· POSTTRANSPLANT IMMUNE MONITORING/SURVEILLANCE
· REFERENCES
· 4. Evaluation of the Potential Kidney Transplant Candidates
· KIDNEY TRANSPLANTATION VERSUS DIALYSIS
· KIDNEY TRANSPLANT EVALUATION PROCESS AND GENERAL ASSESSMENT
· EVALUATION BY ORGAN SYSTEM
· PATIENTS WITH SPECIFIC CONDITIONS
· SPECIFIC KIDNEY DISEASE
· END-STAGE KIDNEY DISEASE ASSOCIATED WITH HEMATOLOGIC MALIGNANCY
· HIGHLY SENSITIZED CANDIDATES
· EVALUATION OF PATIENTS FOR A REPEAT TRANSPLANT
· REFERENCES
· 5. Living Donor Evaluation
· GENERAL EVALUATION
· EVALUATION FOR SPECIFIC CONDITIONS
· HEREDITARY RENAL DISEASE
· INFECTIOUS DISEASE SCREENING
· CANCER SCREENING
· PREGNANCY
· MEDICAL CLEARANCE FOR DONOR NEPHRECTOMY
· SURGICAL EVALUATION
· DONOR SAFETY AND LONG-TERM RENAL FUNCTION
· REFERENCES
· 6. Deceased Donor Kidney Allocation, Strategies to Expand the Living Donor Pool, and Waitlist Management
· UNITED NETWORK FOR ORGAN SHARING LISTING CRITERIA
· DECEASED DONOR KIDNEY ALLOCATION SYSTEM IN THE UNITED STATES
· STRATEGIES TO EXPAND THE LIVING DONOR POOL
· Laws, ethics, and financial aspects of living kidney donation
· Patient education
· Living donor options
· Kidney paired donation registries and organ import/export exchange coordination of care
· WAITLIST MANAGEMENT
· Factors affecting waiting time
· Kidney donor options to reduce waiting time
· Waitlist management dynamics
· United Network for Organ Sharing listing status
· ONGOING HEALTH MAINTENANCE AND SCREENING
· Cancer screening
· Acquired cystic kidney disease and renal cell carcinoma screening
· Cardiovascular screening
· Infectious disease screening
· REFERENCES
· 7. Early and Late Posttransplant Graft Dysfunction
· GENERAL ASSESSMENT
· GRAFT DYSFUNCTION IN THE PERIOPERATIVE PERIOD (FIRST POSTOPERATIVE WEEK)
· GRAFT DYSFUNCTION IN THE EARLY POSTTRANSPLANT PERIOD (1 WEEK TO 3 MONTHS POSTTRANSPLANT)
· GRAFT DYSFUNCTION IN THE LATE POSTTRANSPLANT PERIOD (>3 MONTHS)
· REFERENCES
· 8. Glomerular Disease Recurrence After Transplantation
· BACKGROUND
· IMMUNOGLOBULIN A NEPHROPATHY
· Pathophysiology of immunoglobulin A nephropathy in native kidneys
· Recurrence of Immunoglobulin A nephropathy
· Treatment
· FOCAL SEGMENTAL GLOMERULOSCLEROSIS
· Pathophysiology of focal segmental glomerulosclerosis in native kidneys
· Recurrence of focal segmental glomerulosclerosis
· Clinical presentation
· Treatment
· MEMBRANOUS NEPHROPATHY
· Pathophysiology of membranous nephropathy in native kidneys
· Recurrence of membranous nephropathy
· Clinical manifestations
· Treatment
· MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS
· Pathogenesis of membranoproliferative glomerulonephritis in native kidneys
· Recurrence of membranoproliferative glomerulonephritis
· Treatment
· ATYPICAL HEMOLYTIC UREMIC SYNDROME
· Recurrence of atypical hemolytic uremic syndrome
· Clinical presentation
· Treatment
· LUPUS NEPHRITIS
· Pathophysiology of lupus nephritis in native kidneys
· Recurrence of lupus nephritis
· Treatment
· ANTI–GLOMERULAR BASEMENT MEMBRANE DISEASE
· Pathophysiology of anti–glomerular basement membrane disease in native kidneys
· Recurrence of anti–glomerular basement membrane disease
· Treatment
· ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODY–ASSOCIATED VASCULITIS
· Pathophysiology of antineutrophil cytoplasmic autoantibody–associated vasculitis
· Recurrence of antineutrophil cytoplasmic autoantibody–associated vasculitis
· Clinical presentation
· Treatment
· REFERENCES
· 9. Kidney Allograft Biopsy: Banff Classification and Other Transplant Histopathology
· GENERAL OVERVIEW
· BANFF CLASSIFICATION CATEGORIES
· OTHERS (NOT CLASSIFIED UNDER BANFF CATEGORIES)
· REFERENCES
· 10. Common Posttransplant Abnormal Laboratory Findings
· POSTTRANSPLANT ANEMIA
· LEUKOPENIA AND THROMBOCYTOPENIA
· POSTTRANSPLANT ERYTHROCYTOSIS
· COMMON ELECTROLYTE, ACID-BASE, AND CALCIUM AND PHOSPHOROUS ABNORMALITIES
· Hyponatremia
· Hyperkalemia
· Hypokalemia
· Hypocalcemia
· Hypercalcemia
· Hypomagnesemia
· Hypophosphatemia
· Acid-base disorders
· ABNORMAL LIVER FUNCTION TESTS
· REFERENCES
· 11. Mineral and Bone Disorders After Kidney Transplantation
· CALCIUM
· PHOSPHORUS
· PARATHYROID HORMONE
· VITAMIN D
· BONE DISEASE
· Spectrum of bone disease
· REFERENCES
· 12. Urologic Considerations in the Kidney Transplant Patient
· PRETRANSPLANT UROLOGIC CONSIDERATIONS
· THE IMMEDIATE POSTTRANSPLANT PERIOD
· LONG-TERM UROLOGIC CONCERNS
· OTHER UROLOGIC CONSIDERATIONS
· REFERENCES
· 13. Posttransplantation Infectious Complications and Vaccinations
· VACCINATIONS
· INTERNATIONAL TRAVEL VACCINATION RECOMMENDATIONS/WEBSITE
· RISK FACTORS FOR POSTTRANSPLANTATION INFECTIOUS COMPLICATIONS
· TIMETABLE OF POSTTRANSPLANTATION INFECTIOUS COMPLICATIONS
· RECURRENT URINARY TRACT INFECTION WORKUP AND MANAGEMENT
· SCREENING AND MANAGEMENT OF COMMON POSTTRANSPLANTATION VIRAL INFECTIONS
· Cytomegalovirus
· BK polyomavirus
· Commonly encountered viral infections
· Posttransplantation diarrhea and common gastrointestinal infections
· POTENTIAL EXPOSURE TO INFECTIOUS AGENTS: WHAT TO DO
· REFERENCES
· 14. Posttransplantation Cardiovascular Disease
· POSTTRANSPLANTATION HYPERTENSION
· POSTTRANSPLANTATION DYSLIPIDEMIA
· POSTTRANSPLANTATION DIABETES MELLITUS
· General overview
· Screening and management of posttransplantation diabetes mellitus
· POSTTRANSPLANTATION OBESITY
· CIGARETTE SMOKING
· POSTTRANSPLANTATION PROTEINURIA
· REFERENCES
· 15. Posttransplantation Malignancies
· GENERAL OVERVIEW
· SKIN CANCERS
· POSTTRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD)
· KAPOSI SARCOMA
· RENAL CELL CARCINOMA
· COLORECTAL CANCER
· GENERAL MANAGEMENT OF IMMUNOSUPPRESSION
· REFERENCES
· 16. Kidney Transplantation in Dual Organ Transplantation
· KIDNEY ALLOCATION IN DUAL ORGAN TRANSPLANTATION
· SIMULTANEOUS LIVER-KIDNEY TRANSPLANTATION
· TRANSPLANT OPTIONS FOR TYPE I DIABETICS WITH DIABETIC END-STAGE KIDNEY DISEASE
· SIMULTANEOUS HEART-KIDNEY TRANSPLANTATION
· REFERENCES
· 17. Nutrition Care for Adult Kidney Transplant Candidates and Recipients
· NUTRITION: GENERAL OVERVIEW
· PRETRANSPLANT
· Nutrition assessment pretransplant
· Nutrition-related evaluation/waitlist concerns
· Malnutrition
· Metabolic Bone Disease
· Adherence
· POSTTRANSPLANT
· Early concerns (first 6-8 weeks posttransplant period)
· Nutrient needs
· Postoperative feeding
· Nutrient-drug interactions/side effects
· Food safety
· Long-term concerns
· Cardiovascular disease (CVD) and hypertension
· Weight management
· Osteoporosis/posttransplant bone disease
· Herbal supplements
· Prebiotics/probiotics
· Alcohol
· Special considerations
· Bariatric Surgery
· REFERENCES
· 18. Management of Patients with a Failed Transplant
· TIMING OF DIALYSIS REINITIATION
· IMMUNOSUPPRESSION MANAGEMENT
· GRAFT INTOLERANCE SYNDROME
· INDICATIONS FOR ALLOGRAFT NEPHRECTOMY
· THE IMPACT OF GRAFT NEPHRECTOMY ON A REPEAT TRANSPLANT
· ALLOGRAFT NEPHRECTOMY IN PATIENTS WITH GRAFT LOSS DUE TO BK NEPHROPATHY
· REFERENCES
· 19. Modern Age Transplantation Issues
· ORGAN TRAFFICKING AND TRANSPLANT TOURISM
· MARIJUANA IN TRANSPLANTATION
· Overview
· Marijuana policy
· “Medical marijuana”
· Cannabis use disorder
· Marijuana harms
· REFERENCES
· 20. Frequently Asked Questions
· REFERENCES
An aparitie | 2019 |
Autor | Dr. Phuong-Chi T. Pham MD |
Dimensiuni | 6 x 0.5 x 9 inches |
Editura | Lippincott Williams and Wilkins |
Format | Paperback |
ISBN | 9781496399649 |
Limba | Engleza |
Nr pag | 352 |
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