Gordis Epidemiology, 6e: with STUDENT CONSULT Online Access

Description:

From the Department of Epidemiology at Johns Hopkins University and continuing in the tradition of award-winning educator and epidemiologist Dr. Leon Gordis, comes the fully revised 6th Edition of Gordis Epidemiology. This bestselling text provides a solid introduction to basic epidemiologic principles as well as practical applications in public health and clinical practice, highlighted by real-world examples throughout. New coverage includes expanded information on genetic epidemiology, epidemiology and public policy, and ethical and professional issues in epidemiology, providing a strong basis for understanding the role and importance of epidemiology in today’s data-driven society.

Table of Contents:

1.    Introduction

2.    Chapter 1 Introduction

3.    What Is Epidemiology?

4.    Objectives of Epidemiology

5.    Epidemiology and Prevention

6.    Epidemiology and Clinical Practice

7.    Epidemiologic Approach

8.    From Observations to Preventive Actions

9.    When the Frequency of a Disease Declines, Who Deserves the Credit?

10.  Integrating Prevention and Treatment

11.  Conclusion

12.  References

13.  Chapter 2 The Dynamics of Disease Transmission

14.  Modes of Transmission

15.  Clinical and Subclinical Disease

16.  Carrier Status

17.  Endemic, Epidemic, and Pandemic

18.  Disease Outbreaks

19.  Immunity and Susceptibility

20.  Herd Immunity

21.  Incubation Period

22.  Attack Rate

23.  Exploring Occurrence of Disease

24.  Outbreak Investigation

25.  Conclusion

26.  References

27.  Review Questions for Chapter 2

28.  Chapter 3 The Occurrence of Disease

29.  Surveillance

30.  Stages of Disease in an Individual and in a Population

31.  Measures of Morbidity

32.  Conclusion

33.  References

34.  Review Questions for Chapter 3

35.  Chapter 4 The Occurrence of Disease

36.  Measures of Mortality

37.  Comparing Mortality in Different Populations

38.  Other Measures of the Impact of Disease

39.  Conclusion

40.  References

41.  Review Questions for Chapter 4

42.  Chapter 5 Assessing the Validity and Reliability of Diagnostic and Screening Tests

43.  Biologic Variation of Human Populations

44.  Validity of Screening Tests

45.  Use of Multiple Tests

46.  Predictive Value of a Test

47.  Reliability (Repeatability) of Tests

48.  Relationship Between Validity and Reliability

49.  Conclusion

50.  References

51.  Appendices to Chapter 5

52.  Review Questions for Chapter 5

53.  Chapter 6 The Natural History of Disease

54.  Case-Fatality

55.  Person-Years

56.  Five-Year Survival

57.  Observed Survival

58.  The Kaplan-Meier Method

59.  Assumptions Made in Using Life Tables and Kaplan-Meier Method

60.  Apparent Effects on Prognosis of Improvements in Diagnosis

61.  Median Survival Time

62.  Relative Survival

63.  Generalizability of Survival Data

64.  Conclusion

65.  References

66.  Review Questions for Chapter 6

67.  Section II Using Epidemiology to Identify the Cause of Disease

68.  Introduction

69.  Chapter 7 Observational Studies

70.  Case Reports and Case Series

71.  Ecologic Studies

72.  Cross-Sectional Studies

73.  Case-Control Studies

74.  Conclusion

75.  References

76.  Review Questions for Chapter 7

77.  Chapter 8 Cohort Studies

78.  Design of a Cohort Study

79.  Selection of Study Populations

80.  Types of Cohort Studies

81.  Examples of Cohort Studies

82.  Cohort Studies for Investigating Childhood Health and Disease

83.  Potential Biases in Cohort Studies

84.  When Is a Cohort Study Warranted?

85.  Case-Control Studies Based Within a Defined Cohort

86.  Conclusion

87.  References

88.  Review Questions for Chapter 8

89.  Chapter 9 Comparing Cohort and Case-Control Studies

90.  Chapter 10 Assessing Preventive and Therapeutic Measures

91.  Selection of Subjects

92.  Allocating Subjects to Treatment Groups Without Randomization

93.  Allocating Subjects Using Randomization

94.  Data Collection on Subjects

95.  Crossover

96.  Factorial Design

97.  Noncompliance

98.  Conclusion

99.  References

100.               Chapter 11 Randomized Trials

101.               Sample Size

102.               Recruitment and Retention of Study Participants

103.               Ways of Expressing the Results of Randomized Trials

104.               Interpreting the Results of Randomized Trials

105.               Four Phases in Testing New Drugs in the United States

106.               Five Major Randomized Trials in the United States

107.               Randomized Trials for Evaluating Widely Accepted Interventions

108.               Registration of Clinical Trials

109.               Ethical Considerations

110.               Conclusion

111.               Epilogue

112.               References

113.               Review Questions for Chapters 10 and 11

114.               Chapter 12 Estimating Risk

115.               Absolute Risk

116.               How Do We Determine Whether a Certain Disease Is Associated With a Certain Exposure?

117.               Relative Risk

118.               Odds Ratio (Relative Odds)

119.               Conclusion

120.               References

121.               Review Questions for Chapter 12

122.               Appendix to Chapter 12

123.               Chapter 13 More on Risk

124.               Attributable Risk

125.               Comparison of Relative Risk and Attributable Risk

126.               Conclusion

127.               References

128.               Review Questions for Chapter 13

129.               Appendix to Chapter 13: Levin's Formula for the Attributable Risk for the Total Population

130.               Chapter 14 From Association to Causation

131.               Approaches for Studying Disease Etiology

132.               Types of Associations

133.               Types of Causal Relationships

134.               Evidence for a Causal Relationship

135.               Guidelines for Judging Whether an Observed Association Is Causal

136.               Deriving Causal Inferences: Two Examples

137.               Modifications of the Guidelines for Causal Inferences

138.               Conclusion

139.               References

140.               Review Questions for Chapter 14

141.               Chapter 15 More on Causal Inference

142.               Bias

143.               Confounding

144.               Interaction

145.               Conclusion

146.               References

147.               Review Questions for Chapter 15

148.               Chapter 16 Identifying the Roles of Genetic and Environmental Factors in Disease Causation

149.               Traditional Genetics

150.               Complex Diseases

151.               Time Trends in Disease Incidence

152.               Linkage Analysis in Family Studies

153.               Interaction Between Genetic and Environmental Risk Factors

154.               Precision Medicine

155.               Prospects for the Future

156.               Conclusion

157.               References

158.               Review Questions for Chapter 16

159.               Glossary of Genetic Terms for Chapter 16

160.               Section III Applying Epidemiology to Evaluation and Policy

161.               Introduction

162.               Chapter 17 Using Epidemiology to Evaluate Health Services

163.               Studies of Process and Outcome

164.               Efficacy, Effectiveness, and Efficiency

165.               Measures of Outcome

166.               Comparing Epidemiologic Studies of Disease Etiology and Epidemiologic Research Evaluating Effectiveness of Health Services

167.               Evaluation Using Group Data

168.               Evaluation Using Individual Data

169.               Conclusion

170.               References

171.               Review Questions for Chapter 17

172.               Chapter 18 Epidemiologic Approach to Evaluating Screening Programs

173.               Natural History of Disease

174.               Pattern of Disease Progression

175.               Methodologic Issues

176.               Study Designs for Evaluating Screening: Nonrandomized and Randomized Studies

177.               Problems in Assessing the Sensitivity and Specificity of Screening Tests

178.               Interpreting Study Results That Show No Benefit of Screening

179.               Cost-Benefit Analysis of Screening

180.               Conclusion

181.               References

182.               Review Questions for Chapter 18

183.               Chapter 19 Epidemiology and Public Policy

184.               Epidemiology and Prevention

185.               Population Approaches Versus High-Risk Approaches to Prevention

186.               Epidemiology and Clinical Medicine: Hormone Replacement Therapy in Postmenopausal Women

187.               Risk Assessment

188.               Meta-Analysis

189.               Publication Bias

190.               Epidemiology in the Courts

191.               Sources and Impact of Uncertainty

192.               Policy Issues Regarding Risk: What Should the Objectives Be?

193.               Conclusion

194.               References

195.               Chapter 20 Ethical and Professional Issues in Epidemiology

196.               Ethical Issues in Epidemiology

197.               Investigators’ Obligations to Study Subjects

198.               Protecting Privacy and Confidentiality

199.               Access to Data

200.               Race and Ethnicity in Epidemiologic Studies

201.               Conflict of Interest

202.               Interpreting Findings

203.               Conclusion

204.               References

205.               Answers to Review Questions

206.               Index