Basic and Clinical Pharmacology 14th Edition

The most up-to-date, comprehensive, and authoritative pharmacology text in health medicine—enhanced by a new full-color illustrations
Organized to reflect the syllabi in many pharmacology courses and in integrated curricula, Basic & Clinical Pharmacology, Fourteenth Edition covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. Selection of the subject matter and order of its presentation are based on the authors’ many years’ experience in teaching this material to thousands of medical, pharmacy, dental, podiatry, nursing, and other health science students.
To be as clinically relevant as possible, the book includes sections that specifically address the clinical choice and use of drugs in patients and the monitoring of their effects, and case studies that introduce clinical problems in many chapters. Presented in full color and enhanced by more than three hundred illustrations (many new to this edition), Basic & Clinical Pharmacology features numerous summary tables and diagrams that encapsulate important information.
• Student-acclaimed summary tables conclude each chapter
• Everything students need to know about the science of pharmacology and its application to clinical practice
• Strong emphasis on drug groups and prototypes
• NEW! 100 new drug tables
• Includes 330 full-color illustrations, case studies, and chapter-ending summary tables
• Organized to reflect the syllabi of pharmacology courses
• Descriptions of important new drugs

Table of Contents:

Section I Basic Principles

1. Introduction: The Nature of Drugs & Drug Development & Regulation

2. Drug Receptors & Pharmacodynamics

3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action

4. Drug Biotransformation

5. Pharmacogenomics

Section II Autonomic Drugs

6. Introduction to Autonomic Pharmacology

7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs

8. Cholinoceptor-Blocking Drugs

9. Adrenoceptor Agonists & Sympathomimetic Drugs

10. Adrenoceptor Antagonist Drugs

Section III Cardiovascular-Renal Drugs

11. Antihypertensive Agents

12. Vasodilators & the Treatment of Angina Pectoris

13. Drugs Used in Heart Failure

14. Agents Used in Cardiac Arrhythmias

15. Diuretic Agents

Section IV Drugs with Important Actions on Smooth Muscle

16. Histamine, Serotonin, & the Ergot Alkaloids

17. Vasoactive Peptides

18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds

19. Nitric Oxide

20. Drugs Used in Asthma

Section V Drugs That Act in The Central Nervous System

21. Introduction to the Pharmacology of CNS Drugs

22. Sedative-Hypnotic Drugs

23. The Alcohols

24. Antiseizure Drugs

25. General Anesthetics

26. Local Anesthetics

27. Skeletal Muscle Relaxants

28. Pharmacologic Management of Parkinsonism & Other Movement Disorders

29. Antipsychotic Agents & Lithium

30. Antidepressant Agents

31. Opioid Agonists & Antagonists

32. Drugs of Abuse

Section VI Drugs Used to Treat Diseases of The Blood, Inflammation, & Gout

33. Agents Used in Cytopenias; Hematopoietic Growth Factors

34. Drugs Used in Disorders of Coagulation

35. Agents Used in Dyslipidemia

36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout

Section VII Endocrine Drugs

37. Hypothalamic & Pituitary Hormones

38. Thyroid & Antithyroid Drugs

39. Adrenocorticosteroids & Adrenocortical Antagonists

40. The Gonadal Hormones & Inhibitors

41. Pancreatic Hormones & Antidiabetic Drugs

42. Agents That Affect Bone Mineral Homeostasis

Section VIII Chemotherapeutic Drugs

43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics

44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones

45. Aminoglycosides & Spectinomycin

46. Sulfonamides, Trimethoprim, & Quinolones

47. Antimycobacterial Drugs

48. Antifungal Agents

49. Antiviral Agents

50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants

51. Clinical Use of Antimicrobial Agents

52. Antiprotozoal Drugs

53. Clinical Pharmacology of the Antihelminthic Drugs

54. Cancer Chemotherapy

55. Immunopharmacology

Section IX Toxicology

56. Introduction to Toxicology: Occupational & Environmental

57. Heavy Metal Intoxication & Chelators

58. Management of the Poisoned Patient

Section X Special Topics

59. Special Aspects of Perinatal & Pediatric Pharmacology

60. Special Aspects of Geriatric Pharmacology

61. Dermatologic Pharmacology

62. Drugs Used in the Treatment of Gastrointestinal Diseases

63. Therapeutic & Toxic Potential of Over-the-Counter Agents

64. Dietary Supplements & Herbal Medications

65. Rational Prescribing & Prescription Writing

66. Important Drug Interactions & Their Mechanisms

Appendix: Vaccines, Immune Globulins, & Other Complex Biologic Products

Index