Principles of Pulmonary Medicine

Using a concise, understandable approach, Principles of Pulmonary Medicine, 8th Edition, provides a broad overview of this fast-changing field, integrating clinical topics with underlying physiologic, pathophysiologic, and basic science concepts. From cover to cover, it clearly explains and illustrates even the most challenging concepts in a uniquely readable and digestible fashion. With its emphasis on pathophysiology and diagnosis as the basis for optimal management of respiratory disorders, this popular text is an essential reference for medical students, trainees, and those looking for a practical update on both acute and chronic pulmonary diseases.

Table of Contents:

1.  Pulmonary anatomy and physiology: The basics

Anatomy

Physiology

Abnormalities in gas exchange

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2.  Presentation of the patient with pulmonary disease

Dyspnea

Cough

Hemoptysis

Chest pain

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3.  Evaluation of the patient with pulmonary disease

Evaluation on a macroscopic level

Evaluation on a microscopic level

Assessment on a functional level

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4.  Anatomic and physiologic aspects of airways

Structure

Function

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5.  Asthma

Etiology and pathogenesis

Pathology

Pathophysiology

Clinical features

Diagnostic approach

Treatment

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6.  Chronic obstructive pulmonary disease

Etiology and pathogenesis

Pathology

Pathophysiology

Clinical features

Diagnostic approach and assessment

Treatment

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7.  Miscellaneous airway diseases

Bronchiectasis

Cystic fibrosis

Upper airway disease

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8.  Anatomic and physiologic aspects of the pulmonary parenchyma

Anatomy

Physiology

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9.  Overview of diffuse parenchymal lung diseases

Pathology

Pathogenesis

Pathophysiology

Clinical features

Diagnostic approach

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10.  Diffuse parenchymal lung diseases associated with known etiologic agents

Diseases caused by inhaled inorganic dusts

Hypersensitivity pneumonitis

Drug-induced parenchymal lung disease

Radiation-induced lung disease

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11.  Diffuse parenchymal lung diseases of unknown etiology

Idiopathic pulmonary fibrosis

Other idiopathic interstitial pneumonias

Pulmonary parenchymal involvement complicating systemic rheumatic disease

Sarcoidosis

Miscellaneous disorders involving the pulmonary parenchyma

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12.  Anatomic and physiologic aspects of the pulmonary vasculature

Anatomy

Physiology

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13.  Pulmonary embolism

Etiology and pathogenesis

Pathology

Pathophysiology

Clinical features

Diagnostic evaluation

Treatment

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14.  Pulmonary hypertension

Pathogenesis

Pathology

Pathophysiology

Clinical features

Diagnostic features

Specific disorders associated with pulmonary hypertension

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15.  Pleural disease

Anatomy

Physiology

Pleural effusion

Pneumothorax

Malignant mesothelioma

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16.  Mediastinal disease

Anatomic features

Mediastinal masses

Pneumomediastinum

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17.  Anatomic and physiologic aspects of neural, muscular, and chest wall interactions with the lungs

Respiratory control

Respiratory muscles

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18.  Disorders of ventilatory control

Primary neurologic disease

Cheyne-stokes breathing

Control abnormalities secondary to lung disease

Sleep apnea syndrome

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19.  Disorders of the respiratory pump

Neuromuscular disease affecting the muscles of respiration

Diaphragmatic disease

Disorders affecting the chest wall

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20.  Lung cancer: Etiologic and pathologic aspects

Etiology and pathogenesis

Pathology

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21.  Lung cancer: Clinical aspects

Clinical features

Diagnostic approach

Principles of therapy

Bronchial carcinoid tumors

Solitary pulmonary nodule

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22.  Lung defense mechanisms

Physical or anatomic factors

Antimicrobial peptides

Phagocytic and inflammatory cells

Adaptive immune responses

Failure of respiratory defense mechanisms

Augmentation of respiratory defense mechanisms

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23.  Pneumonia

Etiology and pathogenesis

Pathology

Pathophysiology

Clinical features and initial diagnosis

Therapeutic approach: General principles and antibiotic susceptibility

Initial management strategies based on clinical setting of pneumonia

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24.  Bacterial and viral organisms causing pneumonia

Bacteria

Viruses

Intrathoracic complications of pneumonia

Respiratory infections associated with bioterrorism

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25.  Tuberculosis and nontuberculous mycobacteria

Etiology and pathogenesis

Definitions

Pathology

Pathophysiology

Clinical manifestations

Diagnostic approach

Principles of therapy

Nontuberculous mycobacteria

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26.  Miscellaneous infections caused by fungi, including Pneumocystis

Fungal infections

Pneumocystis infection

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27.  Pulmonary complications in the immunocompromised host

Acquired immunodeficiency syndrome

Pulmonary complications in non–HIV immunocompromised patients

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28.  Classification and pathophysiologic aspects of respiratory failure

Definition of respiratory failure

Classification of acute respiratory failure

Presentation of gas exchange failure

Pathogenesis of gas exchange abnormalities

Clinical and therapeutic aspects of hypercapnic/hypoxemic respiratory failure

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29.  Acute respiratory distress syndrome

Physiology of fluid movement in alveolar interstitium

Etiology

Pathogenesis

Pathology

Pathophysiology

Clinical features

Diagnostic approach

Treatment

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30.  Management of respiratory failure

Goals and principles underlying supportive therapy

Mechanical ventilation

Selected aspects of therapy for chronic respiratory failure

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Appendix A.  Sample problems using respiratory equations

Appendix B.  Pulmonary function tests: Guidelines for interpretation and sample problems

Appendix C.  Arterial blood gases: Guidelines for interpretation and sample problems

Index

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