Infections in Hematology

• A clinically oriented, compact, and up-to-date overview on all aspects of infections in hematology patients
• Identifies the typical pathogens to be considered in different subgroups of patients
• Presents clinical, imaging and laboratory-based diagnostic techniques and discusses the therapeutic strategies appropriate to different situations
• Considers various prophylactic strategies

About this book

Infections are among the most frequent complications in patients with hematological malignancies and in those undergoing high-dose chemotherapy and autologous hematopoietic stem cell transplantation. A profound knowledge on the epidemiology, diagnostic approaches, treatment modalities and prophylactic strategies is essential for the clinical management of these complications in patients who are often severely immunocompromised owing to their underlying diseases and in particular, the intensive myelosuppressive chemo and immunotherapy. This textbook provides a clinically oriented, compact and up-to-date overview on infections in hematology patients and their management. The typical pathogens to be considered in different subgroups of patients are identified and further aspects of the microbiological background are explored.

Clinical, imaging, and laboratory-based diagnostic techniques are discussed and therapeutic strategies appropriate to different situations are then presented, with due attention to the pitfalls, toxicities and interactions that can arise during antimicrobial treatment. Strategies to prevent infection are also outlined, encompassing antimicrobial prophylaxis, isolation procedures, hospital hygiene, protective immunization and the use of hematopoietic growth factors.

Reviews

“This is a comprehensive review of the risk factors, microbiology, prophylaxis, and management of infections in patients with hematological malignancies. … The audience includes students, residents, and practitioners who care for patients with hematological malignancies, and the book targets this group well. … Physicians who care for patients with hematological malignancies need a book like this to give them a comprehensive overview of the support and management of infections in these patients.” (Joseph C. Alvarnas, Doody's Book Reviews, May, 2015)

Table of contents (18 chapters)

·         Infections in Patients with Acute Leukemia

Rolston, Kenneth V. I.

Pages 3-23

·         Infections in Patients with Malignant Lymphomas

Rolston, Kenneth V. I.

Pages 25-37

·         Consequences from Specific Treatment Modalities

Maschmeyer, Georg

Pages 39-47

·         Infections After High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation

Nucci, Marcio (et al.)

Pages 49-61

·         Microbiological Background

Akova, Murat

Pages 63-87

·         The Diagnostic Approach to the Febrile Neutropenic Patient: Clinical Considerations

Bow, Eric J.

Pages 91-111

·         Diagnostic Radiology in Hematological Patients with Febrile Neutropenia

Heussel, Claus Peter

Pages 113-135

·         Risk Stratification in Febrile Neutropenic Patients

Paesmans, Marianne

Pages 137-152

·         Fever of Unknown Origin: Treatment According to Risk Assessment

Maschmeyer, Georg

Pages 155-163

·         Pulmonary Complications

Maschmeyer, Georg

Pages 165-185

·         Vascular Catheter-Related Infections

Dababneh, Luma (et al.)

Pages 187-195

·         Gastrointestinal Complications

Blijlevens, Nicole M. A.

Pages 197-210

·         Central Nervous System Infections

Schmidt-Hieber, Martin

Pages 211-226

·         Antibacterial Agents

Kern, Winfried V.

Pages 229-258

·         Antifungal Agents

Thompson, George R. (et al.)

Pages 259-272

·         Antimicrobial Prophylaxis in Hematology

Girmenia, Corrado (et al.)

Pages 275-296

·         Infection Control and Hospital Epidemiology in Hematology Units

Weisser, Maja (et al.)

Pages 297-313

·         Myeloid Growth Factors

Link, Hartmut

Pages 315-324