Goodman and Gilman Manual of Pharmacology and Therapeutics

Description:

A full-color manual derived from Goodman & Gilman's The Pharmacological Basis of Therapeutics Goodman & Gilman's The Manual of Pharmacology and Therapeutics offers concise, authoritative coverage of class-specific and disease-specific drugs, organized primarily by organ/system. Derived from Goodman & Gilman's Pharmacological Basis of Therapeutics, Twelfth Edition and further updated, this streamlined text focuses on the principles of medical pharmacology and drug therapy and delivers coverage of all major drug classes. More than a pocket drug guide, this powerful resource covers: General Principles Neuropharmacology Modulation of Cardiovascular, Pulmonary, and Renal Function Inflammation, Immunomodulation, and Hematopoiesis Hormones and Hormone Antagonists Drugs Affecting Gastrointestinal Function Chemotherapy of Microbial Diseases Chemotherapy of Neoplastic Diseases Special Systems Pharmacology, including Environmental Toxicology The text explains the physiology and pathophysiology of major organ systems and pathogens with respect to pharmacotherapy and the mechanisms of drug action. With a new full color design and numerous tables, charts, and illustrations that highlight, explain, and summarize important information, Goodman & Gilman's Manual of Pharmacology and Therapeutics is essential wherever knowledge of drug actions and interactions is required. Nursing, pharmacy, and medical students will find the Manual to be a concise and authoritative textbook.

Table of Contents:

Section I General Principles

1. Drug Invention and the Pharmaceutical Industry

2. Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination

3. Pharmacodynamics: Molecular Mechanisms of Drug Action

4. Drug Toxicity and Poisoning

5. Membrane Transporters and Drug Response

6. Drug Metabolism

7. Pharmacogenetics

Section II Neuropharmacology

8. Neurotransmission: The Autonomic and Somatic Motor Nervous Systems

9. Muscarinic Receptor Agonists and Antagonists

10. Anticholinesterase Agents

11. Agents Acting at the Neuromuscular Junction and Autonomic Ganglia

12. Adrenergic Agonists and Antagonists

13. 5-Hydroxytryptamine (Serotonin) and Dopamine

14. Neurotransmission and the Central Nervous System

15. Drug Therapy of Depression and Anxiety Disorders

16. Pharmacotherapy of Psychosis and Mania

17. Hypnotics and Sedatives

18. Opioids, Analgesia, and Pain Management

19. General Anesthetics and Therapeutic Gases

20. Local Anesthetics

21. Pharmacotherapy of the Epilepsies

22. Treatment of Central Nervous System Degenerative Disorders

23. Ethanol and Methanol

24. Drug Addiction

Section III Modulation of Cardiovascular Function

25. Regulation of Renal Function and Vascular Volume

26. Renin and Angiotensin

27. Treatment of Myocardial Ischemia and Hypertension

28. Pharmacotherapy of Congestive Heart Failure

29. Anti-Arrhythmic Drugs

30. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs

31. Drug Therapy for Hypercholesterolemia and Dyslipidemia

Section IV Inflammation, Immunomodulation, and Hematopoiesis

32. Histamine, Bradykinin, and Their Antagonists

33. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor

34. Pharmacotherapy of Inflammation, Fever, Pain, and Gout

35. Immunosuppressants, Tolerogens, and Immunostimulants

36. Pulmonary Pharmacology

37. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins

Section V Hormones and Hormone Antagonists

38. Introduction to Endocrinology: The Hypothalamic-Pituitary Axis

39. Thyroid and Anti-Thyroid Drugs

40. Estrogens and Progestins

41. Androgens

42. Pharmacology of the Adrenal Cortex

43. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia

44. Agents Affecting Mineral Ion Homeostasis and Bone Turnover

Section VI Drugs Affecting Gastrointestinal Function

45. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease

46. Gastrointestinal Motility and Water Flux; Emesis; Biliary and Pancreatic Disease

47. Pharmacotherapy of Inflammatory Bowel Disease

Section VII Chemotherapy of Microbial Diseases

48. General Principles of Antimicrobial Therapy

49. Chemotherapy of Malaria

50. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections

51. Chemotherapy of Helminth Infections

52. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections

53. Penicillins, Cephalosporins, and Other β-Lactam Antibiotics

54. Aminoglycosides

55. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents

56. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy

57. Antifungal Agents

58. Antiviral Agents (Nonretroviral)

59. Antiretroviral Agents and Treatment of HIV Infection

Section VIII Chemotherapy of Neoplastic Diseases

60. General Principles of Cancer Chemotherapy

61. Cytotoxic Agents

62. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines

63. Natural Products in Cancer Chemotherapy: Hormones and Related Agents

Section IX Special Systems Pharmacology

64. Ocular Pharmacology

65. Dermatological Pharmacology

66. Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders

67. Environmental Toxicology: Carcinogens and Heavy Metals

Appendix I Principles of Prescription Order Writing and Patient Compliance

Index