Drug-induced Neurological Disorders

Description:

This book is a first-of-its kind reference that systematically organizes and describes the adverse effects of drugs on the nervous system. Drug safety is recognized as an important aspect of pharmaceutical companies as well as practice of medicine.  Chapters include case reports of adverse effects of drugs that are published as well as reported to drug manufacturers. The book scope is broad as it covers lack of efficacy, drug resistance, drug-disease and drug-drug interactions. This information is used to improve the use of drugs as well as to design better and safer drugs for the future, and is relevant to personalized medicine in trying to match the right drugs to the patients. Drug-induced Neurological Disorders offers a unique approach to this important topic by integrating clinical neurology with pharmacology with a focus on effects of drugs on the nervous system including those used for the treatment of neurological disorders as well systemic diseases. Many adverse effects involve multiple systems of the body and the syndromes with predominant effect on the nervous system are included in this book.

Table of contents:

Cover

Front Matter

Part I. Basics of Adverse Drug Reactions of the Nervous System

1. Introduction, History, and Epidemiology of Drug-Induced Neurological Disorders

2. Neurologic Symptoms as Adverse Drug Reactions

3. Role of the Blood-Brain Barrier in Effects of Drugs on the Brain

4. Pathomechanisms of Drug-Induced Neurological Disorders

5. Adverse Effects of Drugs on the Fetal Nervous System

6. Principles of Management of Drug-Induced Neurological Disorders

Part II. Neurological Complications of Therapies

7. Methods of Drug Delivery to the Nervous System and DIND

8. Neurological Complications of Anesthesia

9. Neurological Complications of Cancer Therapies

10. Adverse Effects of Biological Therapies on the Nervous System

Part III. Drug-Induced Neurological Disorders

11. Drug-Induced Aseptic Meningitis

12. Drug-Induced Intracranial Hypertension

13. Drug-Induced Encephalopathies

14. Drug-Induced Disorders of Memory and Dementia

15. Drug-Induced Disturbances of Consciousness

16. Drug-Induced Neuropsychiatric Disorders

17. Neurologic Effects of Drug Abuse

18. Drug-Induced Sleep Disorders

19. Drug-Induced Seizures

20. Drug-Induced Movement Disorders

21. Tardive Dyskinesia

22. Drug-Induced Headaches

23. Drug-Induced Cerebrovascular Disorders

24. Drug-Induced Disorders of Cranial Nerves

25. Drug-Induced Neurootological Disorders

26. Drug-Induced Neuro-ophthalmological Disorders

27. Drug-Induced Disorders of Smell and Taste

28. Drug-Induced Peripheral Neuropathies

29. Drug-Induced Disorders of the Autonomic Nervous System

30. Drug-Induced Neuromuscular Disorders

31. Drug-Induced Myopathies

32. Drug-Induced Spinal Disorders

33. Drug-Induced Cerebellar Disorders

34. Eosinophilia-Myalgia Syndrome

35. Drug-Induced Pituitary Disorders

36. Serotonin Syndrome

37. Drug-Induced Guillain-Barré Syndrome

38. Neuroleptic Malignant Syndrome

Back Matter